All Phenotypes Arhgef5<tm1.2Meg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Arhgef5^tm1.2Meg
targeted mutation 1.2, Michael E Greenberg
MGI:4882035

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arhgef5^tm1.2Meg/Arhgef5^tm1.2Meg	involves: 129S4/SvJae	MGI:4882043

Allelic Composition	Arhgef5^tm1.2Meg/Arhgef5^tm1.2Meg
Genetic Background	involves: 129S4/SvJae

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arhgef5^tm1.2Meg mutation (0 available); any Arhgef5 mutation (72 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

increased CNS synapse formation ( J:167914 )

• in cultured neurons

• the CA1 stratum radiatum exhibits a 2-fold increase in the number of excitatory synapses compared to in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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