homeostasis/metabolism
• increased levels of asymmetric dimethyl arginine in lung, liver, and kidney
• symmetric dimethyl arginine is elevated by about 60% only in lung
|
• increased levels of asymmetric dimethyl arginine in plasma
|
• acetylcholine induced stimulation of NO production in isolated aortic rings is attenuated
|
cardiovascular system
N |
• cardiac structure and function is normal
|
• including aortic systolic pressure
|
• isolated aortic ring relaxation is reduced
|
muscle
• isolated aortic ring relaxation is reduced
|