Phenotypes associated with this allele

• Allele Symbol: Gnas^tm3Jop
• Allele Name: targeted mutation 3, Jo Peters
• Allele ID: MGI:4887403
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Gnas^tm3Jop/Gnas^+	involves: 129S/SvEv	MGI:5317112

Genotype
MGI:5317112

ht1

• Allelic Composition: Gnas^tm3Jop/Gnas⁺
• Genetic Background: involves: 129S/SvEv

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:182868 )

• 93% survival past weaning

growth/size/body

decreased birth weight ( J:182868 )

• 95% of control weight when paternally inherited

decreased lean body mass ( J:182868 )

• reduced lean body mass at 12 weeks when paternally inherited but not significant

slow postnatal weight gain ( J:182868 )

• weight is 83% of normal controls at 2 weeks when paternally inherited

• weight is 96% of normal controls at 7-12 weeks (near normal)

adipose tissue

decreased total body fat amount ( J:182868 )

• reduced total body fat at 12 weeks of age when paternally inherited but not significant

behavior/neurological

behavior/neurological phenotype ( J:182868 )

N • suckling behavior normal

abnormal eating behavior ( J:182868 )

• eat less when paternally inherited