Analysis Tools
nervous system
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• mice exhibit normal gross morphology and neuronal density in the hippocampus
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• increased excitatory and inhibitory synapse density
• however, thickness and perforation are normal and re-expression of the endogenous gene rescues excitatory synapse numbers
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• increased in the density and length of postsynaptic density apposed to presynaptic vesicle
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• increased mEPSC frequency but not amplitude
• however, frequency is rescued by re-expression of the endogenous gene
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• increased mIPSC frequency but not amplitude
• however, re-expression of the endogenous gene does not rescue mIPSC frequency
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