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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dlg4tm4.1Grnt
targeted mutation 4.1, Seth G N Grant
MGI:4888250
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dlg4tm4.1Grnt/Dlg4tm4.1Grnt involves: 129P2/OlaHsd * MF1 MGI:4888258


Genotype
MGI:4888258
hm1
Allelic
Composition		 Dlg4tm4.1Grnt/Dlg4tm4.1Grnt
Genetic
Background		 involves: 129P2/OlaHsd * MF1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dlg4tm4.1Grnt mutation (0 available); any Dlg4 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal nociception after inflammation ( J:168384 )
• following inflammatory injury, mice fail to exhibit an increase in thermal, chemical, or mechanical sensitivity unlike wild-type mice
• however, nociception following chronic constriction injury is normal

nervous system
nervous system phenotype ( J:168384 )
N
• mice exhibit normal synaptic plasticity




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory