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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Fasltm1.1Cgm
targeted mutation 1.1, Geert Michel
MGI:4888490
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Fasltm1.1Cgm/Fasltm1.1Cgm involves: 129S2/SvPas * C57BL/6 * C57BL/6N MGI:4888492


Genotype
MGI:4888492
hm1
Allelic
Composition
Fasltm1.1Cgm/Fasltm1.1Cgm
Genetic
Background
involves: 129S2/SvPas * C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fasltm1.1Cgm mutation (1 available); any Fasl mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• lymphocytes exhibit normal induced apoptosis
• activation-induced lymphocyte proliferation is increased compared to in wild-type mice
• activation-induced lymphocyte proliferation is increased compared to in wild-type mice
• following stimulation with NP-CGG
• following stimulation with NP-CGG or NP-Ficoll
• following stimulation with NP-CGG or NP-Ficoll

hematopoietic system
• activation-induced lymphocyte proliferation is increased compared to in wild-type mice
• activation-induced lymphocyte proliferation is increased compared to in wild-type mice
• following stimulation with NP-CGG
• following stimulation with NP-CGG or NP-Ficoll
• following stimulation with NP-CGG or NP-Ficoll

cellular
• activation-induced lymphocyte proliferation is increased compared to in wild-type mice
• activation-induced lymphocyte proliferation is increased compared to in wild-type mice





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory