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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Emx2wndr
wanderer
MGI:4888743
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Emx2wndr/Emx2wndr
Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw 		involves: BALB/c * C57BL/6 * C57BL/6J * FVB/N MGI:4889074


Genotype
MGI:4889074
cx1
Allelic
Composition		 Emx2wndr/Emx2wndr
Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw
Genetic
Background		 involves: BALB/c * C57BL/6 * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx2wndr mutation (0 available); any Emx2 mutation (24 available)
Tg(Mbp-MAPT/lacZ)#aCaw mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:168258 )
• mice die within a few hours of birth

nervous system
abnormal axon extension ( J:168258 )
• thalamocortical axons exhibit severe ventral misrouting near the diencephalon-telencephalon boundary on the ventral surface compared with wild-type mice
abnormal cerebral cortex morphology ( J:168258 )
• small and misshapen
small olfactory bulb ( J:168258 )
• small and misshapen

renal/urinary system

cellular
abnormal axon extension ( J:168258 )
• thalamocortical axons exhibit severe ventral misrouting near the diencephalon-telencephalon boundary on the ventral surface compared with wild-type mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory