Phenotypes associated with this allele

• Allele Symbol: bumpy
• Allele Name: bumpy
• Allele ID: MGI:4889057
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	bumpy/bumpy Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw	involves: BALB/c * C57BL/6 * C57BL/6J * FVB/N	MGI:4889077

Genotype
MGI:4889077

cx1

• Allelic Composition: bumpy/bumpy; Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw
• Genetic Background: involves: BALB/c * C57BL/6 * C57BL/6J * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:168258 )

nervous system

abnormal axon extension ( J:168258 )

abnormal axon fasciculation ( J:168258 )

• thalamocortical axons exhibit fascicles to ectopia outside pia unlike in wild-type mice

abnormal forebrain morphology ( J:168258 )

• the forebrain has a cobblestone surface unlike in wild-type mice

limbs/digits/tail

short tail ( J:168258 )

• stunted

cellular

abnormal axon extension ( J:168258 )

abnormal axon fasciculation ( J:168258 )

• thalamocortical axons exhibit fascicles to ectopia outside pia unlike in wild-type mice