Phenotypes associated with this allele

• Allele Symbol: Tg(CD2-Lmo2)#Thr
• Allele Name: transgene insertion, Terence H Rabbitts
• Allele ID: MGI:4889196
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(CD2-Lmo2)#Thr/0	involves: C57BL/6 * CBA	MGI:4889198

Genotype
MGI:4889198

tg1

• Allelic Composition: Tg(CD2-Lmo2)#Thr/0
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:102058 )

• mice die from acute lymphoblastic leukemia unlike wild-type mice

immune system

enlarged thymus ( J:102058 )

enlarged spleen ( J:102058 )

neoplasm

increased acute lymphoblastic leukemia incidence ( J:102058 )

• mice die from acute lymphoblastic leukemia unlike wild-type mice

hematopoietic system

enlarged thymus ( J:102058 )

enlarged spleen ( J:102058 )

endocrine/exocrine glands

enlarged thymus ( J:102058 )

growth/size/body

enlarged spleen ( J:102058 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
acute lymphoblastic leukemia		DOID:9952	OMIM:247640 OMIM:613065	J:102058