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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(CAG-Rpgr)mROrfWrght
transgene insertion mROrf, Rachel Wright
MGI:4936751
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tg(CAG-Rpgr)mROrfWrght/0
Rpgrtm1Tili/Rpgrtm1Tili 		involves: 129S4/SvJae * C57BL/6J MGI:5313504
cx2
 		Tg(CAG-Rpgr)mROrfWrght/0
Tg(CAG-Rpgr)mRDefWrght/0
Rpgrtm1Tili/Rpgrtm1Tili 		involves: 129S4/SvJae * C57BL/6J MGI:5313506


Genotype
MGI:5313504
cx1
Allelic
Composition		 Tg(CAG-Rpgr)mROrfWrght/0
Rpgrtm1Tili/Rpgrtm1Tili
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rpgrtm1Tili mutation (0 available); any Rpgr mutation (10 available)
Tg(CAG-Rpgr)mROrfWrght mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
vision/eye phenotype ( J:181417 )
N
• mutants do not exhibit measurable photoreceptor degeneration at 3 months of age
• cone opsins are localized normally




Genotype
MGI:5313506
cx2
Allelic
Composition		 Tg(CAG-Rpgr)mROrfWrght/0
Tg(CAG-Rpgr)mRDefWrght/0
Rpgrtm1Tili/Rpgrtm1Tili
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rpgrtm1Tili mutation (0 available); any Rpgr mutation (10 available)
Tg(CAG-Rpgr)mRDefWrght mutation (0 available)
Tg(CAG-Rpgr)mROrfWrght mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
retina photoreceptor degeneration ( J:181417 )
• retinal cell degeneration is rapid with complete loss of photoreceptors by 8 months of age

nervous system
retina photoreceptor degeneration ( J:181417 )
• retinal cell degeneration is rapid with complete loss of photoreceptors by 8 months of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory