All Phenotypes Mecp2<tm3.1Bird> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mecp2^tm3.1Bird
targeted mutation 3.1, Adrian Bird
MGI:4938309

Summary

3 genotypes

Allelic Composition	Mecp2^tm3.1Bird/Mecp2^tm3.1Bird
Genetic Background	involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2^tm3.1Bird mutation (1 available); any Mecp2 mutation (41 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:168822 )

• mice are viable, fertile, and normal in size and do not display any gross physical or behavioral abnormalities

Allelic Composition	Mecp2^tm3.1Bird/Y
Genetic Background	involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2^tm3.1Bird mutation (1 available); any Mecp2 mutation (41 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:168822 )

• mice are viable, fertile, and normal in size and do not display any gross physical or behavioral abnormalities

Allelic Composition	Mecp2^tm3.1Bird/Y
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2^tm3.1Bird mutation (1 available); any Mecp2 mutation (41 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

• slightly increased latency to fall in hanging wire test

growth/size/body

decreased body weight ( J:227401 )

• weight gain is less than wild-type litter mates when measured collectively (Repeated Measures ANOVA), but not at single time points

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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