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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nlrc5tm1Aki
targeted mutation 1, Shizuo Akira
MGI:4939792
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nlrc5tm1Aki/Nlrc5tm1Aki Not Specified MGI:4939793


Genotype
MGI:4939793
hm1
Allelic
Composition		 Nlrc5tm1Aki/Nlrc5tm1Aki
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlrc5tm1Aki mutation (0 available); any Nlrc5 mutation (67 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:168788 )
N
• mice exhibit normal inflammatory cytokine and type I IFN production in response to stimulation with agonists for Toll-like receptor, RIG-I-like receptor, and a DNA sensor
• mice exhibit normal IL1b production after stimulation or infection with NLRP3 and AIM2 activators or bacteria




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory