All Phenotypes Ren1<tm1.1Sig> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ren1^tm1.1Sig
targeted mutation 1.1, Curt Sigmund
MGI:4939805

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ren1^tm1.1Sig/Ren1^tm1.1Sig Tg(Nes-cre)1Kln/0	involves: C57BL/6 * C57BL/6J * SJL	MGI:4939887
cn2	Ren1^tm1.1Sig/Ren1^tm1.1Sig Tg(GFAP-cre)25Mes/0	involves: C57BL/6J * FVB/N	MGI:4939886

Allelic Composition	Ren1^tm1.1Sig/Ren1^tm1.1Sig Tg(Nes-cre)1Kln/0
Genetic Background	involves: C57BL/6 * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ren1^tm1.1Sig mutation (0 available); any Ren1 mutation (35 available)
Tg(Nes-cre)1Kln mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:168753 )

N	• mice exhibit normal survival unlike Ren1^tm1.2Sig homozygotes

renal/urinary system

renal/urinary system phenotype ( J:168753 )

N	• mice exhibit normal renal morphology and function

cardiovascular system

cardiovascular system phenotype ( J:168753 )

N	• mice exhibit normal blood pressure

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:168753 )

N	• mice exhibit normal metabolism

Allelic Composition	Ren1^tm1.1Sig/Ren1^tm1.1Sig Tg(GFAP-cre)25Mes/0
Genetic Background	involves: C57BL/6J * FVB/N