Phenotypes associated with this allele

• Allele Symbol: Tomm6^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4940754
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tomm6^tm1a(KOMP)Wtsi/Tomm6^tm1a(KOMP)Wtsi	C57BL/6N-Tomm6^tm1a(KOMP)Wtsi/Wtsi	MGI:6731465
ht2	Tomm6^tm1a(KOMP)Wtsi/Tomm6^+	C57BL/6N-Tomm6^tm1a(KOMP)Wtsi/Wtsi	MGI:6679313

Genotype
MGI:6731465

hm1

• Allelic Composition: Tomm6^{tm1a(KOMP)Wtsi}/Tomm6^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Tomm6^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0735_3_B03

Data Sources

IMPC Data for Tomm6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

no spontaneous movement ( J:211773 )

IMPC - CCP-IMG

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - CCP-IMG

Genotype
MGI:6679313

ht2

• Allelic Composition: Tomm6^{tm1a(KOMP)Wtsi}/Tomm6⁺
• Genetic Background: C57BL/6N-Tomm6^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0735_3_B03

Data Sources

IMPC Data for Tomm6

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

digestive/alimentary system

abnormal salivary gland morphology ( J:211773 )

♂

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal salivary gland morphology ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - CCP-IMG

increased circulating lactate dehydrogenase level ( J:211773 )

♂

IMPC - CCP-IMG

immune system

abnormal lymph node morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged lymph nodes ( J:211773 )

♂

IMPC - CCP-IMG