Phenotypes associated with this allele

• Allele Symbol: Sema4b^tm1Akum
• Allele Name: targeted mutation 1, Atsushi Kumanogoh
• Allele ID: MGI:4941169
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sema4b^tm1Akum/Sema4b^tm1Akum	either: B6.Cg-Sema4b^tm1Akum or C.Cg-Sema4b^tm1Akum	MGI:4941177

Genotype
MGI:4941177

hm1

• Allelic Composition: Sema4b^tm1Akum/Sema4b^tm1Akum
• Genetic Background: either: B6.Cg-Sema4b^tm1Akum or C.Cg-Sema4b^tm1Akum

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal immune system physiology ( J:169386 )

• mice exhibit enhanced memory response compared with wild-type mice

• however, deletion of basophils suppresses this enhancement

increased IgE level ( J:169386 )

• following immunization with NP-CGG or Fcer1 cross-linking

• following immunization and boost with ovalbumin

increased IgG1 level ( J:169386 )

• following immunization and boost with ovalbumin

hematopoietic system

increased IgE level ( J:169386 )

• following immunization with NP-CGG or Fcer1 cross-linking

• following immunization and boost with ovalbumin

increased IgG1 level ( J:169386 )

• following immunization and boost with ovalbumin