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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Thy1-QPCT)#Tbay
transgene insertion, Thomas A Bayer
MGI:4941713
Summary 2 genotypes


Genotype
MGI:4941719
cx1
Allelic
Composition		 Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas/0
Tg(Thy1-QPCT)#Tbay/0
Genetic
Background		 B6.Cg-Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas Tg(Thy1-QPCT)#Tbay
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas mutation (16 available)
Tg(Thy1-QPCT)#Tbay mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal spatial working memory ( J:169481 )
• mice exhibit decreased alternation frequency in a Y maze compared with Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas mice
impaired coordination ( J:169481 )
• mice exhibit impaired motor coordination on a beam or when suspended by a string compared with Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas mice

nervous system
amyloid beta deposits ( J:169481 )
• at 6 months, mice exhibit a higher plaque load than Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas mice

homeostasis/metabolism
amyloid beta deposits ( J:169481 )
• at 6 months, mice exhibit a higher plaque load than Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas mice




Genotype
MGI:4941716
tg2
Allelic
Composition		 Tg(Thy1-QPCT)#Tbay/0
Genetic
Background		 B6.Cg-Tg(Thy1-QPCT)#Tbay
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:169481 )
N
• mice exhibit normal motor coordination and spatial working memory




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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory