All Phenotypes Plekha2<tm1.1Arte> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Plekha2^tm1.1Arte
targeted mutation 1.1, TaconicArtemis
MGI:4941747

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plekha2^tm1.1Arte/Plekha2^tm1.1Arte	C57BL/6J-Plekha2^tm1.1Arte	MGI:4941750
cx2	Plekha1^tm1.1Arte/Plekha1^tm1.1Arte Plekha2^tm1.1Arte/Plekha2^tm1.1Arte	C57BL/6J-Plekha1^tm1.1Arte Plekha2^tm1.1Arte	MGI:4941751

Allelic Composition	Plekha2^tm1.1Arte/Plekha2^tm1.1Arte
Genetic Background	C57BL/6J-Plekha2^tm1.1Arte

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plekha2^tm1.1Arte mutation (0 available); any Plekha2 mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:169475 )

• mice are viable

Allelic Composition	Plekha1^tm1.1Arte/Plekha1^tm1.1Arte Plekha2^tm1.1Arte/Plekha2^tm1.1Arte
Genetic Background	C57BL/6J-Plekha1^tm1.1Arte Plekha2^tm1.1Arte

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plekha1^tm1.1Arte mutation (0 available); any Plekha1 mutation (54 available)
Plekha2^tm1.1Arte mutation (0 available); any Plekha2 mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

increased cardiac muscle cell glucose uptake ( J:169475 )

• glucose uptake in the heart is increased compared to in wild-type mice

increased skeletal muscle cell glucose uptake ( J:169475 )

• glucose uptake in the gastrocnemius is increased compared to in wild-type mice

homeostasis/metabolism

increased insulin sensitivity ( J:169475 )

cardiovascular system

increased cardiac muscle cell glucose uptake ( J:169475 )

• glucose uptake in the heart is increased compared to in wild-type mice

cellular

increased cardiac muscle cell glucose uptake ( J:169475 )

• glucose uptake in the heart is increased compared to in wild-type mice

increased skeletal muscle cell glucose uptake ( J:169475 )

• glucose uptake in the gastrocnemius is increased compared to in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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