Phenotypes associated with this allele

• Allele Symbol: Slc5a7^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4942035
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc5a7^tm1a(KOMP)Wtsi/Slc5a7^tm1a(KOMP)Wtsi	C57BL/6N-Slc5a7^tm1a(KOMP)Wtsi/Wtsi	MGI:5631554
ht2	Slc5a7^tm1a(KOMP)Wtsi/Slc5a7^+	C57BL/6N-Slc5a7^tm1a(KOMP)Wtsi/Wtsi	MGI:5706096

Genotype
MGI:5631554

hm1

• Allelic Composition: Slc5a7^{tm1a(KOMP)Wtsi}/Slc5a7^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Slc5a7^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0742_5_H10

Data Sources

IMPC Data for Slc5a7

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal vertebral artery topology ( J:239583 )

DMDD

abnormal coronary sinus connection ( J:239583 )

DMDD

muscular ventricular septal defect ( J:239583 )

DMDD

bicuspid aortic valve ( J:239583 )

DMDD

digestive/alimentary system

dilated pancreatic duct ( J:239583 )

DMDD

abnormal small intestine morphology ( J:239583 )

DMDD

endocrine/exocrine glands

dilated pancreatic duct ( J:239583 )

DMDD

immune system

blood in lymph vessels ( J:239583 )

DMDD

liver/biliary system

herniated liver ( J:239583 )

DMDD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

normal phenotype

no abnormal phenotype detected ( J:239583 )

DMDD

vision/eye

abnormal eye morphology ( J:239583 )

DMDD

retrolental blood ( J:239583 )

DMDD

Genotype
MGI:5706096

ht2

• Allelic Composition: Slc5a7^{tm1a(KOMP)Wtsi}/Slc5a7⁺
• Genetic Background: C57BL/6N-Slc5a7^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0742_5_H10

Data Sources

IMPC Data for Slc5a7

adipose tissue

decreased total body fat amount ( J:211773 )

♂

IMPC - WTSI

behavior/neurological

increased grip strength ( J:211773 )

IMPC - WTSI

homeostasis/metabolism

decreased circulating fructosamine level ( J:211773 )

♂

IMPC - WTSI

integument

abnormal hair growth ( J:211773 )

♂

IMPC - WTSI