Phenotypes associated with this allele

• Allele Symbol: Ndufs4^fky
• Allele Name: funky
• Allele ID: MGI:4942335
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ndufs4^fky/Ndufs4^fky	C57BL/6-Ndufs4^fky	MGI:5432784

Genotype
MGI:5432784

hm1

• Allelic Composition: Ndufs4^fky/Ndufs4^fky
• Genetic Background: C57BL/6-Ndufs4^fky

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Ndufs4^fky/Ndufs4^fky mice have transient hair loss

mortality/aging

premature death ( J:186512 )

• from P40 onward, mice required euthanasia due to rapidly progressing neurological symptoms

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:186512 )

• from P40 onward, mice required euthanasia due to rapidly progressing neurological symptoms

limb grasping ( J:186512 )

• from 5 weeks onward

head tilt ( J:186512 )

• from 5 weeks onward

circling ( J:186512 )

• from 5 weeks onward

homeostasis/metabolism

increased circulating carnitine level ( J:186512 )

• increased hydroxyacylcarnitines in the blood

increased circulating glycine level ( J:186512 )

• increased glycine in the blood

increased circulating homocitrulline level ( J:186512 )

• increased homocitrulline in the blood

increased circulating phenylalanine level ( J:186512 )

• increased phenylalanine in the blood

growth/size/body

decreased body size ( J:186512 )

• at P40

postnatal growth retardation ( J:186512 )

• from postnatal week 2

integument

focal hair loss ( J:186512 )

• at P16 in the neck area

• hair loss spreads caudally along the trunk towards the tail