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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Pcsk9tm1.1Prat
targeted mutation 1.1, Annik Prat
MGI:4943284
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Pcsk9tm1.1Prat/Pcsk9tm1.1Prat
Speer6-ps1Tg(Alb-cre)21Mgn/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA MGI:4943540


Genotype
MGI:4943540
cn1
Allelic
Composition
Pcsk9tm1.1Prat/Pcsk9tm1.1Prat
Speer6-ps1Tg(Alb-cre)21Mgn/?
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pcsk9tm1.1Prat mutation (0 available); any Pcsk9 mutation (46 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• total plasma cholesterol reduced 27%
• plasma levels are 70% of levels in controls
• plasma levels are 40% of levels in controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory