All Phenotypes Maoa<tm1Shih> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Maoa^tm1Shih
targeted mutation 1, Jean C Shih
MGI:4946240

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Maoa^tm1Shih/Maoa^tm1Shih	involves: 129S4/SvJae	MGI:4946255

Allelic Composition	Maoa^tm1Shih/Maoa^tm1Shih
Genetic Background	involves: 129S4/SvJae

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Maoa^tm1Shih mutation (1 available); any Maoa mutation (11 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

decreased left ventricle systolic pressure ( J:170067 )

• before and after transverse aortic constriction

abnormal myocardial fiber physiology ( J:170067 )

• myocytes treated with norepinephrine exhibit reduced reactive oxygen species formation compared with similarly treated wild-type mice

decreased response of heart to induced stress ( J:170067 )

• at 9 weeks after transverse aortic constriction, mice exhibit improved left ventricular function, no chamber dilation, and reduced levels of fibrosis compared with wild-type mice

homeostasis/metabolism

decreased response of heart to induced stress ( J:170067 )

• at 9 weeks after transverse aortic constriction, mice exhibit improved left ventricular function, no chamber dilation, and reduced levels of fibrosis compared with wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24