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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ciao3tm1.1Fsl
targeted mutation 1.1, Frank Lee
MGI:4946831
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ciao3tm1.1Fsl/Ciao3tm1.1Fsl involves: C57BL/6 * C57BL/6NTac MGI:4946834
cn2
 		Ciao3tm1.1Fsl/Ciao3tm1.1Fsl
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+ 		involves: C57BL/6 * C57BL/6NTac MGI:4946835


Genotype
MGI:4946834
hm1
Allelic
Composition		 Ciao3tm1.1Fsl/Ciao3tm1.1Fsl
Genetic
Background		 involves: C57BL/6 * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ciao3tm1.1Fsl mutation (1 available); any Ciao3 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:170523 )
• mice are viable and phenotypically normal




Genotype
MGI:4946835
cn2
Allelic
Composition		 Ciao3tm1.1Fsl/Ciao3tm1.1Fsl
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic
Background		 involves: C57BL/6 * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ciao3tm1.1Fsl mutation (1 available); any Ciao3 mutation (29 available)
Gt(ROSA)26Sortm9(cre/ESR1)Arte mutation (2 available); any Gt(ROSA)26Sor mutation (993 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:170523 )
• all mice die within 5 days of tamoxifen treatment




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory