All Phenotypes Cfap97d1<tm1a(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cfap97d1^{tm1a(KOMP)Wtsi}
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4947739

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cfap97d1^{tm1a(KOMP)Wtsi}/Cfap97d1^{tm1a(KOMP)Wtsi}	involves: 129S/SvEv * C57BL/6N	MGI:6469467

Allelic Composition	Cfap97d1^{tm1a(KOMP)Wtsi}/Cfap97d1^{tm1a(KOMP)Wtsi}
Genetic Background	involves: 129S/SvEv * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cfap97d1^{tm1a(KOMP)Wtsi} mutation (1 available); any Cfap97d1 mutation (11 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:294173 )

N	• female mice exhibit normal fertility

asthenozoospermia ( J:294173 )

• reduced curvilinear velocity and average path velocity with more asymmetrical waveform pattern and reduced beat frequency in the midpiece compared with wild-type sperm

• however, straight-line velocity is normal

reduced male fertility ( J:294173 )

impaired sperm penetration of zona pellucida ( J:294173 )

cellular

asthenozoospermia ( J:294173 )

• reduced curvilinear velocity and average path velocity with more asymmetrical waveform pattern and reduced beat frequency in the midpiece compared with wild-type sperm

• however, straight-line velocity is normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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