mortality/aging
• all mice born die within the first 3 weeks after birth
|
• fewer than expected mice are born
|
growth/size/body
• mice fail to thrive after birth
|
cellular
• endocytosis of Grin2c (NR2C) in cerebellar neurons is impaired compared to in wild-type cells
|
cardiovascular system
small heart
(
J:171001
)
digestive/alimentary system
• small sized intestine
|
hematopoietic system
small spleen
(
J:171001
)
liver/biliary system
small liver
(
J:171001
)
immune system
small spleen
(
J:171001
)