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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Snx27tm1Lslo
targeted mutation 1, Li Shen Loo
MGI:4949192
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Snx27tm1Lslo/Snx27tm1Lslo involves: 129P2/OlaHsd MGI:4949194


Genotype
MGI:4949194
hm1
Allelic
Composition
Snx27tm1Lslo/Snx27tm1Lslo
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Snx27tm1Lslo mutation (0 available); any Snx27 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• all mice born die within the first 3 weeks after birth
• fewer than expected mice are born

growth/size/body
• mice fail to thrive after birth

cellular
• endocytosis of Grin2c (NR2C) in cerebellar neurons is impaired compared to in wild-type cells

cardiovascular system

digestive/alimentary system
• small sized intestine

hematopoietic system

liver/biliary system

immune system





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory