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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prkntm2Tmd
targeted mutation 2, Ted M Dawson
MGI:4949289
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Prkntm2Tmd/Prkntm2Tmd Not Specified MGI:4949296


Genotype
MGI:4949296
cn1
Allelic
Composition		 Prkntm2Tmd/Prkntm2Tmd
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkntm2Tmd mutation (0 available); any Prkn mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased dopaminergic neuron number ( J:171058 )
• following sterotaxic injection of a cre-expressing lentivirus, the number of Nissl+ and TH+ dopaminergic neurons is decreased compared to in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory