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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pkd1l1tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:4949891
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pkd1l1tm1Lex/Pkd1l1tm1Lex involves: 129S5/SvEvBrd * C57BL/6Brd MGI:4950029


Genotype
MGI:4950029
hm1
Allelic
Composition		 Pkd1l1tm1Lex/Pkd1l1tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6Brd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1l1tm1Lex mutation (2 available); any Pkd1l1 mutation (156 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:171184 )
• significantly reduced survival in the early postnatal period or possibly before

growth/size/body
situs inversus ( J:171184 )
• displayed by one third of homozygotes

nervous system
nervous system phenotype ( J:171184 )
N
• normal brain ventricles

embryo
embryo phenotype ( J:171184 )
N
• embryonic cilium function is normal

respiratory system
respiratory system phenotype ( J:171184 )
N
• clear nasal passages

reproductive system
reproductive system phenotype ( J:171184 )
N
• normal fertility




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory