All Phenotypes Gnas/Nespas<tm2.1Jop> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gnas/Nespas^tm2.1Jop
targeted mutation 1.1, Jo Peters
MGI:4950066

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Gnas/Nespas^tm2.1Jop/Gnas⁺	involves: 129S/SvEv * 129S1/Sv	MGI:4950260

Allelic Composition	Gnas/Nespas^tm2.1Jop/Gnas⁺
Genetic Background	involves: 129S/SvEv * 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gnas/Nespas^tm2.1Jop mutation (0 available); any Gnas mutation (54 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal DNA methylation ( J:171195 )

• when this allele is inherited paternally, mice exhibit hypomethylation of the Nesp (Gnas) somatic differentially methylated region (DMR) compared with wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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