Analysis Tools|
Allele Symbol Allele Name Allele ID |
Ccl2tm1.1Pame targeted mutation 1.1 Eric G Pamer MGI:4950271 |
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| Summary |
4 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• LPS-induced monocyte emigration is decreased compared to in similarly treated wild-type mice
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
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• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
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• LPS-induced monocyte emigration is decreased compared to in similarly treated wild-type mice
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
|
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• LPS-induced monocyte emigration is decreased compared to in similarly treated wild-type mice
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• LPS-treated mice exhibit reduced percent of circulating Ly6Chi monocyte compared with similarly treated wild-type mice
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
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• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow and diminished bacterial clearance compared with similarly treated wild-type mice
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• LPS-treated mice exhibit reduced percent of circulating Ly6Chi monocyte compared with similarly treated wild-type mice
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
|
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• LPS-treated mice exhibit reduced percent of circulating Ly6Chi monocyte compared with similarly treated wild-type mice
• mice exposed to L. monocytogenes exhibit reduced Ly6Chi monocyte emigration from the bone marrow compared with similarly treated wild-type mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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