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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Foxp3tm1(CD2/CD52)Shori
targeted mutation 1, Shohei Hori
MGI:4950682
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Foxp3tm1(CD2/CD52)Shori/Foxp3tm1(CD2/CD52)Shori involves: C57BL/6 MGI:4950700


Genotype
MGI:4950700
hm1
Allelic
Composition		 Foxp3tm1(CD2/CD52)Shori/Foxp3tm1(CD2/CD52)Shori
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxp3tm1(CD2/CD52)Shori mutation (1 available); any Foxp3 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased regulatory T cell number ( J:171378 )
• in mabcampath-treated mice
increased susceptibility to type IV hypersensitivity reaction ( J:171378 )
• in mice treated with mabcampath and UV-irradiated

hematopoietic system
decreased regulatory T cell number ( J:171378 )
• in mabcampath-treated mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory