All Phenotypes Hdac2<tm1.1Eem> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Hdac2^tm1.1Eem
targeted mutation 1.1, Edward E Morrisey
MGI:4950697

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Hdac2^tm1.1Eem/Hdac2^tm1.1Eem Pou5f1^tm2Jae/?	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6	MGI:4950699

Allelic Composition	Hdac2^tm1.1Eem/Hdac2^tm1.1Eem Pou5f1^tm2Jae/?
Genetic Background	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hdac2^tm1.1Eem mutation (0 available); any Hdac2 mutation (40 available)
Pou5f1^tm2Jae mutation (1 available); any Pou5f1 mutation (82 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal cell physiology ( J:171358 )

• mouse embryonic fibroblasts transduced with a cre-expressing adenovirus and a Mir302/367-expressing virus form Pou5f1-GFP+ produce viable induced pluripotent stem cells (iPSCs) unlike wild-type cells in the absence of valproic acid

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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