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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zfp830tm2.1Cota
targeted mutation 2.1, Michel Cohen-Tannoudji
MGI:4950702
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Zfp830tm1Cota/Zfp830tm2.1Cota involves: 129S2/SvPas * BALB/c * C57BL/6 MGI:4950718
cn2
 		Zfp830tm2.1Cota/Zfp830tm2.2Cota
Gt(ROSA)26Sortm2(cre/ERT2)Brn/? 		involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6 MGI:4950720


Genotype
MGI:4950718
ht1
Allelic
Composition		 Zfp830tm1Cota/Zfp830tm2.1Cota
Genetic
Background		 involves: 129S2/SvPas * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfp830tm1Cota mutation (0 available); any Zfp830 mutation (14 available)
Zfp830tm2.1Cota mutation (0 available); any Zfp830 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:171647 )
• mice exhibit no phenotype




Genotype
MGI:4950720
cn2
Allelic
Composition		 Zfp830tm2.1Cota/Zfp830tm2.2Cota
Gt(ROSA)26Sortm2(cre/ERT2)Brn/?
Genetic
Background		 involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(cre/ERT2)Brn mutation (1 available); any Gt(ROSA)26Sor mutation (993 available)
Zfp830tm2.1Cota mutation (0 available); any Zfp830 mutation (14 available)
Zfp830tm2.2Cota mutation (0 available); any Zfp830 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
decreased cell proliferation ( J:171647 )
• in tamoxifen-treated fibroblasts
early cellular replicative senescence ( J:171647 )
• proliferation of mouse embryonic fibroblasts is arrested 24 hours after tamoxifen-treatment unlike in control cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory