Phenotypes associated with this allele

• Allele Symbol: Gnl3^{Gt(S4-4B1)Sor}
• Allele Name: gene trap S4-4B1, Philippe Soriano
• Allele ID: MGI:4974804
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gnl3^Gt(S4-4B1)Sor/Gnl3^Gt(S4-4B1)Sor	involves: 129S4/SvJaeSor * C57BL/6	MGI:5428143

Genotype
MGI:5428143

hm1

• Allelic Composition: Gnl3^{Gt(S4-4B1)Sor}/Gnl3^{Gt(S4-4B1)Sor}
• Genetic Background: involves: 129S4/SvJaeSor * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Impaired perimplantation development of Gnl3^{Gt(S4-4B1)Sor}/Gnl3^{Gt(S4-4B1)Sor} embryos

mortality/aging

embryonic lethality, complete penetrance ( J:185271 )

• mice die between E3.5 to E7.5

embryo

embryonic growth retardation ( J:185271 )

• at E3.5

absent blastocoele ( J:185271 )

absent inner cell mass ( J:185271 )

absent trophectoderm ( J:185271 )

cellular

increased apoptosis ( J:185271 )

• at E3.5

decreased cell proliferation ( J:185271 )

• at E3.5

growth/size/body

embryonic growth retardation ( J:185271 )

• at E3.5