Phenotypes associated with this allele

• Allele Symbol: Hcrtr1^tm1Mmsc
• Allele Name: targeted mutation 1, Michael M Scott
• Allele ID: MGI:5000034
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hcrtr1^tm1Mmsc/Hcrtr1^tm1Mmsc	B6.Cg-Hcrtr1^tm1Mmsc	MGI:5000035

Genotype
MGI:5000035

hm1

• Allelic Composition: Hcrtr1^tm1Mmsc/Hcrtr1^tm1Mmsc
• Genetic Background: B6.Cg-Hcrtr1^tm1Mmsc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:171751 )

N • no significant differences in anxiety related behavior or activity in a novel environment are detected

abnormal depression-related behavior ( J:171751 )

• significant reduction in time immobile and increase in latency to first bout of immobility in a forced swim test suggesting a decrease in depression like behavior

• immobility is also reduced in a tail suspension test