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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm2.1(MYC/ERT)Hsc
targeted mutation 2.1, Hubert Schorle
MGI:5000148
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Gt(ROSA)26Sortm2.1(MYC/ERT)Hsc/Gt(ROSA)26Sor+ involves: 129P2/OlaHsd * 129S4/SvJaeSor MGI:5000221


Genotype
MGI:5000221
ht1
Allelic
Composition		 Gt(ROSA)26Sortm2.1(MYC/ERT)Hsc/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJaeSor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2.1(MYC/ERT)Hsc mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
increased cell proliferation ( J:89756 )
• in cultured neural crest cells treated with tamoxifen
• however, removal of tamoxifen restores normal proliferation and differentiation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory