Analysis Tools
mortality/aging
|
• mice die of unknown causes at 20 to 24 months of age
|
behavior/neurological
abnormal gait
(
J:89772
)
|
• at 18 months, male mice exhibit impaired gait compared with control mice
• however, female mice do not exhibit impaired gait
|
|
• at 22 months, male mice exhibit hindlimb paralysis unlike control mice
• however, female mice do not exhibit severe hindlimb paralysis
|
growth/size/body
|
• beginning at 12 months of age in male mice and 22 months of age in female mice
|
|
• beginning at 12 months of age in male mice and 22 months of age in female mice
|
muscle
|
• at 18 months, male mice exhibit hindlimb atrophy unlike control mice
• however, female mice do not exhibit severe hindlimb atrophy
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| Kennedy's disease | DOID:0060161 |
OMIM:313200 |
J:89772 | |
