Phenotypes associated with this allele

• Allele Symbol: mul
• Allele Name: mullet
• Allele ID: MGI:5004963
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	mul/mul	involves: 129S1/Sv * C57BL/6 * FVB/NJ	MGI:5006952

Genotype
MGI:5006952

hm1

• Allelic Composition: mul/mul
• Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/NJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Exencephaly and craniorachischisis in E9.5-10.5 mul/mul embryos

mortality/aging

perinatal lethality, complete penetrance ( J:171522 )

• embryos are viable until late gestation (E18.5)

cardiovascular system

cardiovascular system phenotype ( J:171522 )

N • no overt vascular patterning anomalies were detected in E10.5 mullet embryos based on PECAM-1 immunostaining

craniofacial

small pharyngeal arch ( J:171522 )

• at E10.5, only minor or subtle reductions in pharyngeal arch size are observed

embryo

small pharyngeal arch ( J:171522 )

• at E10.5, only minor or subtle reductions in pharyngeal arch size are observed

decreased embryo size ( J:171522 )

• at E10.5, mutant embryos are slightly smaller than control littermates

craniorachischisis ( J:171522 )

• rostral crainorachischesis

growth/size/body

decreased embryo size ( J:171522 )

• at E10.5, mutant embryos are slightly smaller than control littermates

nervous system

abnormal nervous system development ( J:171522 )

• at E10.5, mutant embryos show defects in peripheral nervous system patterning

craniorachischisis ( J:171522 )

• rostral crainorachischesis

exencephaly ( J:171522 )

• exencephaly with open and everted neural folds

abnormal glossopharyngeal ganglion morphology ( J:171522 )

• at E10.5, discontinuity between the glossopharyngeal ganglion and the hindbrain and spinal cord is seen

abnormal trigeminal ganglion morphology ( J:171522 )

• at E10.5, reduction and hypoplasia of the maxillary branch of the trigeminal ganglion is seen