All Phenotypes Il10<tm1Keny> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Il10^tm1Keny
targeted mutation 1, Kenya Honda
MGI:5005059

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Il10^tm1Keny/Il10⁺ Nfil3^tm1.1Kubo/Nfil3^tm1.1Kubo	involves: 129 * C57BL/6	MGI:5006686

Allelic Composition	Il10^tm1Keny/Il10⁺ Nfil3^tm1.1Kubo/Nfil3^tm1.1Kubo
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il10^tm1Keny mutation (0 available); any Il10 mutation (45 available)
Nfil3^tm1.1Kubo mutation (1 available); any Nfil3 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased interleukin-10 secretion ( J:172134 )

• following MOG-treatment, fewer Il10+ T cells are detected in the spleen, intestinal intraepithelial lymphocytes, lamina propria, and bone marrow compared to in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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