All Phenotypes Il10<tm1Keny> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Il10^tm1Keny
targeted mutation 1, Kenya Honda
MGI:5005059

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Il10^tm1Keny/Il10⁺ Nfil3^tm1.1Kubo/Nfil3^tm1.1Kubo	involves: 129 * C57BL/6	MGI:5006686

Allelic Composition	Il10^tm1Keny/Il10⁺ Nfil3^tm1.1Kubo/Nfil3^tm1.1Kubo
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il10^tm1Keny mutation (0 available); any Il10 mutation (45 available)
Nfil3^tm1.1Kubo mutation (1 available); any Nfil3 mutation (32 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased interleukin-10 secretion ( J:172134 )

• following MOG-treatment, fewer Il10+ T cells are detected in the spleen, intestinal intraepithelial lymphocytes, lamina propria, and bone marrow compared to in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24