immune system
• in a T cell transfer model of colitis, mice receiving T cells from knock-out mice exhibit decreased body weight and worse clinical colitis score compared with mice receiving wild-type T cells
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• invariant NK T cells from the spleen or thymus co-cultured with bone marrow-derived dendritic cells exhibit reduced production of IL9, IL10. IL13, IL17a and IL22 compared with wild-type cells
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• in stimulated T cells, regulatory T cells, and NKT cells
(J:172134)
• in invariant NK T cells from the spleen or thymus co-cultured with bone marrow-derived dendritic cells
(J:184570)
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• in stimulated T cells and NKT cells
(J:172134)
• in invariant NK T cells from the spleen or thymus co-cultured with bone marrow-derived dendritic cells
(J:184570)
|
• in invariant NK T cells from the spleen or thymus co-cultured with bone marrow-derived dendritic cells
|
• in invariant NK T cells from the spleen or thymus co-cultured with bone marrow-derived dendritic cells
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• mice fail to recover form MOG-induced experimental autoimmune encephalomyelitis unlike wild-type mice
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digestive/alimentary system
N |
• mice show no significant differences in the colonic expression of Lncucc1 (ulcerative colitis circadian clock long noncoding RNA 1) or its rhythmicity at 6 circadian time points relative to wild-type controls
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• in a T cell transfer model of colitis, mice receiving T cells from knock-out mice exhibit decreased body weight and worse clinical colitis score compared with mice receiving wild-type T cells
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growth/size/body
• in a T cell transfer model of colitis, mice receiving T cells from knock-out mice exhibit decreased body weight compared with mice receiving wild-type T cells
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