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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gpr15lgtm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5006994
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gpr15lgtm1Lex/Gpr15lgtm1Lex B6;129S5-Gpr15lgtm1Lex/Mmucd MGI:5827827


Genotype
MGI:5827827
hm1
Allelic
Composition		 Gpr15lgtm1Lex/Gpr15lgtm1Lex
Genetic
Background		 B6;129S5-Gpr15lgtm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpr15lgtm1Lex mutation (2 available); any Gpr15lg mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased IgG2a level ( J:171883 )
• homozygous mutant mice exhibited an increased mean serum IgG2a response to ovalbumin challenge when compared with that of their wild-type littermates

immune system
increased IgG2a level ( J:171883 )
• homozygous mutant mice exhibited an increased mean serum IgG2a response to ovalbumin challenge when compared with that of their wild-type littermates




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory