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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Emc7tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5006995
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Emc7tm1Lex/Emc7tm1Lex B6;129S5-Emc7tm1Lex/Mmucd MGI:5827831
ht2
 		Emc7tm1Lex/Emc7+ B6;129S5-Emc7tm1Lex/Mmucd MGI:5827834


Genotype
MGI:5827831
hm1
Allelic
Composition		 Emc7tm1Lex/Emc7tm1Lex
Genetic
Background		 B6;129S5-Emc7tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emc7tm1Lex mutation (1 available); any Emc7 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality ( J:171883 )
• homozygous lethal




Genotype
MGI:5827834
ht2
Allelic
Composition		 Emc7tm1Lex/Emc7+
Genetic
Background		 B6;129S5-Emc7tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emc7tm1Lex mutation (1 available); any Emc7 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased response to stress-induced hyperthermia ( J:171883 )
• male heterozygous mice exhibited an increased anxiety-like response during stress-induced hyperthermia testing

homeostasis/metabolism
increased response to stress-induced hyperthermia ( J:171883 )
• male heterozygous mice exhibited an increased anxiety-like response during stress-induced hyperthermia testing




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory