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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Chst14tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007062
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Chst14tm1Lex/Chst14tm1Lex B6;129S5-Chst14tm1Lex/Mmucd MGI:5828132


Genotype
MGI:5828132
hm1
Allelic
Composition		 Chst14tm1Lex/Chst14tm1Lex
Genetic
Background		 B6;129S5-Chst14tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chst14tm1Lex mutation (2 available); any Chst14 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
decreased anxiety-related response ( J:171883 )
• male homozygous mutants exhibited a decreased anxiety-like response during stress-induced hyperthermia testing

growth/size/body
decreased body length ( J:171883 )
• decreased mean body length when compared with controls

nervous system
enhanced sensorimotor gating ( J:171883 )
• homozygous mutant mice also exhibited enhanced sensorimotor gating/attention at 3 of 4 prepulse intensities




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory