About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dhrs4tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007107
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dhrs4tm1Lex/Dhrs4tm1Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:5429515


Genotype
MGI:5429515
hm1
Allelic
Composition		 Dhrs4tm1Lex/Dhrs4tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dhrs4tm1Lex mutation (2 available); any Dhrs4 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal humoral immune response ( J:171883 )
• decreased mean serum IgG2a response to ovalbumin challenge when compared with that of controls

behavior/neurological
behavioral despair ( J:171883 )
• female mutants exhibited an increased depressive-like response during tail suspension testing

hematopoietic system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory