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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Lrrc4ctm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007224
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Lrrc4ctm1Lex/Lrrc4ctm1Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:5494674


Genotype
MGI:5494674
hm1
Allelic
Composition
Lrrc4ctm1Lex/Lrrc4ctm1Lex
Genetic
Background
involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrrc4ctm1Lex mutation (2 available); any Lrrc4c mutation (41 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• homozygous mutant mice exhibited an increased mean serum IL-6 response to LPS challenge when compared with controls

immune system
• homozygous mutant mice exhibited an increased mean serum IL-6 response to LPS challenge when compared with controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory