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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nxph4tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007268
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nxph4tm1Lex/Nxph4tm1Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:5430938


Genotype
MGI:5430938
hm1
Allelic
Composition		 Nxph4tm1Lex/Nxph4tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxph4tm1Lex mutation (2 available); any Nxph4 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating triglyceride level ( J:171883 )
• female homozygous mutant mice exhibited a decreased mean serum triglyceride level
increased urine nitrite level ( J:171883 )
• homozygous mutants exhibit nitrituria

renal/urinary system
increased urine nitrite level ( J:171883 )
• homozygous mutants exhibit nitrituria




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory