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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Fam3dtm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007269
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Fam3dtm1Lex/Fam3dtm1Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:5429565


Genotype
MGI:5429565
hm1
Allelic
Composition		 Fam3dtm1Lex/Fam3dtm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fam3dtm1Lex mutation (2 available); any Fam3d mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
decreased depression-related behavior ( J:171883 )
• male homozygous mutant mice exhibit decreased depressive-like response during tail suspension testing
decreased anxiety-related response ( J:171883 )
• male homozygous mutant mice exhibit a decreased anxiety-like response during open field testing




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory