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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Uxs1tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007401
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Uxs1tm1Lex/Uxs1tm1Lex B6;129S5-Uxs1tm1Lex/Mmucd MGI:5428865
ht2
 		Uxs1tm1Lex/Uxs1+ B6;129S5-Uxs1tm1Lex/Mmucd MGI:5428852


Genotype
MGI:5428865
hm1
Allelic
Composition		 Uxs1tm1Lex/Uxs1tm1Lex
Genetic
Background		 B6;129S5-Uxs1tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Uxs1tm1Lex mutation (2 available); any Uxs1 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5428852
ht2
Allelic
Composition		 Uxs1tm1Lex/Uxs1+
Genetic
Background		 B6;129S5-Uxs1tm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Uxs1tm1Lex mutation (2 available); any Uxs1 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased IgG1 level ( J:171883 )
• heterozygous mice exhibited an increased mean serum IgG2a response to ovalbumin challenge when compared with that of controls

hematopoietic system
increased IgG1 level ( J:171883 )
• heterozygous mice exhibited an increased mean serum IgG2a response to ovalbumin challenge when compared with that of controls




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory