Phenotypes associated with this allele

• Allele Symbol: Csrp1^tm1Mbk
• Allele Name: targeted mutation 1, Mary C Beckerle
• Allele ID: MGI:5007641
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Csrp1^tm1Mbk/Csrp1^tm1Mbk	B6.129-Csrp1^tm1Mbk	MGI:5007646
cx2	Csrp1^tm1Mbk/Csrp1^tm1Mbk Csrp2^tm1Sfy/Csrp2^tm1Sfy	involves: 129 * 129S2/SvPas * C57BL/6	MGI:5007647

Genotype
MGI:5007646

hm1

• Allelic Composition: Csrp1^tm1Mbk/Csrp1^tm1Mbk
• Genetic Background: B6.129-Csrp1^tm1Mbk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:172149 )

N • mice exhibit normal blood vessel morphology

N • mice exhibit normal smooth muscle development and contraction

abnormal vascular wound healing ( J:172149 )

• following wire-induced arterial injury, mice exhibit decreased neointima formation compared to in wild-type mice

homeostasis/metabolism

abnormal vascular wound healing ( J:172149 )

• following wire-induced arterial injury, mice exhibit decreased neointima formation compared to in wild-type mice

muscle

muscle phenotype ( J:172149 )

N • mice exhibit normal smooth muscle development and contraction

Genotype
MGI:5007647

cx2

• Allelic Composition: Csrp1^tm1Mbk/Csrp1^tm1Mbk; Csrp2^tm1Sfy/Csrp2^tm1Sfy
• Genetic Background: involves: 129 * 129S2/SvPas * C57BL/6

cardiovascular system

cardiovascular system phenotype ( J:172149 )

N • following wire-induced arterial injury, mice exhibit normal neointima formation