homeostasis/metabolism
• impaired ability to respond to cold exposure
|
• modest when fed a high-fat diet
(J:172245)
• when housed in metabolic cages
(J:198134)
|
• mice fed a high-fat diet exhibit improved glucose homeostasis compared with wild-type mice
• however, mice fed a standard chow diet exhibit normal glucose homeostasis
|
• in fasting mice when fed a high-fat diet
|
• when fed a high-fat diet
|
• when fed a high-fat diet
|
• when fed a high-fat diet, mice exhibit increased plasma levels of adiponectin and resistin compared with wild-type mice
• however, leptin levels are normal
|
• when fed a high-fat diet
|
• when fed a high-fat diet
|
adipose tissue
• brown adipose tissue exhibits an increase in the number of cells with large unilocular lipid droplets similar to white adipose tissue unlike in wild-type mice
|
• when fed a high-fat diet
|
liver/biliary system
• when fed a high-fat diet
|
• when fed a high-fat diet
|
behavior/neurological
• when fed a high-fat diet
(J:172245)
• when housed in metabolic cages
(J:198134)
|
• when housed in metabolic cages
|