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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(LRRK2*Y1699C)#aMjfa
transgene insertion #a, Matthew Farrer
MGI:5008462
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(LRRK2*Y1699C)#aMjfa/0 FVB-Tg(LRRK2*Y1699C)#aMjfa MGI:5008469


Genotype
MGI:5008469
tg1
Allelic
Composition		 Tg(LRRK2*Y1699C)#aMjfa/0
Genetic
Background		 FVB-Tg(LRRK2*Y1699C)#aMjfa
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal axon extension ( J:172418 )
• primary neurons exhibit reduced neuron outgrowth and branching compared with control neurons
• however, indolocarbazole-treatment partially rescues outgrowth
abnormal neurite morphology ( J:172418 )
• primary neurons exhibit reduced neuron outgrowth and branching compared with control neurons
• however, indolocarbazole-treatment partially rescues outgrowth

cellular
abnormal axon extension ( J:172418 )
• primary neurons exhibit reduced neuron outgrowth and branching compared with control neurons
• however, indolocarbazole-treatment partially rescues outgrowth




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory