All Phenotypes Pkd2l1<tm1.1Yuni> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pkd2l1^tm1.1Yuni
targeted mutation 1.1, Yuzo Ninomiya
MGI:5008611

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pkd2l1^tm1.1Yuni/Pkd2l1^tm1.1Yuni	involves: 129S/SvEv * C57BL/6	MGI:5008625
cx2	Gad1^tm1.1Tama/Gad1⁺ Pkd2l1^tm1.1Yuni/Pkd2l1^tm1.1Yuni	involves: 129S/SvEv * C57BL/6 * CBA	MGI:5008624
cx3	Pkd1l3^tm1.1Abek/Pkd1l3^tm1.1Abek Pkd2l1^tm1.1Yuni/Pkd2l1^tm1.1Yuni	involves: 129S/SvEv * C57BL/6 * CBA	MGI:5008626

Allelic Composition	Pkd2l1^tm1.1Yuni/Pkd2l1^tm1.1Yuni
Genetic Background	involves: 129S/SvEv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd2l1^tm1.1Yuni mutation (1 available); any Pkd2l1 mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal nerve fiber response ( J:172581 )

• chorda tympani (CT) nerves response to sour tastants is lower than in wild-type mice

• however, mice exhibit normal CT nerve response to sweet, salty, bitter, and umami compounds and glossopharyngeal nerve response to all tastants

taste/olfaction

abnormal gustatory system physiology ( J:172581 )

• chorda tympani (CT) nerves response to sour tastants is lower than in wild-type mice

• however, mice exhibit normal CT nerve response to sweet, salty, bitter, and umami compounds and glossopharyngeal nerve response to all tastants

Allelic Composition	Gad1^tm1.1Tama/Gad1⁺ Pkd2l1^tm1.1Yuni/Pkd2l1^tm1.1Yuni
Genetic Background	involves: 129S/SvEv * C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gad1^tm1.1Tama mutation (2 available); any Gad1 mutation (65 available)
Pkd2l1^tm1.1Yuni mutation (1 available); any Pkd2l1 mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal nerve fiber response ( J:172581 )

• chorda tympani nerves response to sour tastants is lower than in wild-type mice

taste/olfaction

abnormal gustatory system physiology ( J:172581 )

• chorda tympani nerves response to sour tastants is lower than in wild-type mice

Allelic Composition	Pkd1l3^tm1.1Abek/Pkd1l3^tm1.1Abek Pkd2l1^tm1.1Yuni/Pkd2l1^tm1.1Yuni
Genetic Background	involves: 129S/SvEv * C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1l3^tm1.1Abek mutation (1 available); any Pkd1l3 mutation (154 available)
Pkd2l1^tm1.1Yuni mutation (1 available); any Pkd2l1 mutation (50 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal nerve fiber response ( J:172581 )

• chorda tympani (CT) nerves response to sour tastants is lower than in wild-type mice

• however, mice exhibit normal CT nerve response to sweet, salty, bitter, and umami compounds and glossopharyngeal nerve response to all tastants

taste/olfaction

abnormal gustatory system physiology ( J:172581 )

• chorda tympani (CT) nerves response to sour tastants is lower than in wild-type mice

• however, mice exhibit normal CT nerve response to sweet, salty, bitter, and umami compounds and glossopharyngeal nerve response to all tastants

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24